AJR Am J Roentgenol. 2012 Feb; 198(2): 370-6
Krishnan P, Fiel MI, Rosenkrantz AB, Hajdu CH, Schiano TD, Oyfe I, Taouli B
The purposes of this study were to describe a spectrum of cross-sectional imaging commentary of pathologically proven hepatoportal sclerosis as well as to review a facilities of advanced as well as nonadvanced hepatoportal sclerosis.Eighteen patients with a histopathologic diagnosis of hepatoportal sclerosis who had concurrent MRI or CT images participated in a study. The following imaging facilities were assessed: participation of liver nodularity as well as liver lesions, portal capillary patency, participation as well as degree of portal hypertension, liver volume, as well as caudate-to-right lobe ratio. These facilities were compared between patients who underwent transplant as well as those who did not.The 18 patients (11 men as well as one boy, 6 women; mean age, 46.5 years) had hepatoportal sclerosis confirmed with liver biopsy (14 patients) or explant (four patients). Fourteen patients underwent contrast-enhanced MRI, as well as five underwent CT. The imaging commentary were as follows: liver surface nodularity, five patients (all four transplant, one nontransplant) (p = 0.0016); evidence of portal hypertension, seventeen patients; increasing caudate-to-right lobe ratio, 16 patients; high periportal signal intensity on T2-weighted images, 6 patients; portal capillary occlusion with cavernous transformation, five patients. The transplant patients had not as big pretransplant liver volume than did nontransplant patients (p < 0.04).Hepatoportal sclerosis is characterized by caudate lobe hypertrophy as well as right hepatic lobe atrophy, recorded liver volume, as well as lack of a liver nodularity associated with portal hypertension. In advanced cases, liver nodularity as well as atrophy produce an imaging appearance indistinguishable from that of cirrhosis.
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