Correction of endothelial dysfunction in patients with arterial hypertension.

Bull Exp Biol Med. 2011 Jun; 151(2): 183-5
Soloviev MA, Kulakova NV, Semiglazova TA, Borodulina EV, Udut VV

We examined 38 patients (mean age 55.921.56 years) with a 3-5-year history of arterial hypertension. The study showed that hypertension is accompanied by endothelial dysfunction and a single of the forming factors is activation of the inflammatory response. Highly supportive diagnostic tests can verify initiation of inflammation in preclinical manifestations. The use of nonsteroidal anti-inflammatory drugs, irrespective of the tropism to cyclooxygenase forms, alleviates manifestations of endothelial dysfunction in patients with arterial hypertension.

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