Wednesday, February 1, 2012

Ten years survival with excellent outcome after living donor liver transplantation from 70 years old donor for primary hepatic neuroendocrine carcinoma: Case report.

Int J Surg Case Rep. 2012; 3(1): 34-6
Alekseev D, Goralczyk A, Lorf T, Ramadori G, Obed A

Primary hepatic carcinoid tumors (PHCT) have been rare entities; they have been even rarer than extrahepatic neuroendocrine gastrointestinal tumors with only about 95 cases reported in a literature. An extrahepatic first growth must be excluded to confirm a diagnosis of PHCT.We report a case of a 42-year-old male patient with a first hepatic neuroendocrine carcinoma, who successfully underwent living donor liver transplantation from his 70 years old mother with 10 years follow-up. Both donor and recipient have been still alive and in a great health.Living liver concession from elderly donors for a patients with irresectable neuroendocrine liver malignancies can be as safe as deceased concession or liver concession from young donors (age<50). Living concession from elderly donors might significantly expand a donor pool for patients with liver neuroendocrine tumors (NET) and potentially reduce waiting list mortality. Especially young patients with irresectable NET can benefit from this option. However, case-control studies have been needed to verify a advantage of living liver transplantation (LDLT) for a patients with irresectable liver NET and to conclude selection criteria for these patients.


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